Papillon-Lefevre syndrome (PLS) is an autosomal recessive genetic disorder. It has a reported incidence of 1-4 persons per million. This syndrome presents with dermatological and dental manifestations. It is usually diagnosed by the presence of palmar-plantar hyperkeratosis of the skin and premature exfoliation of the teeth. This case report describes preventive prosthetic treatment given to 17 year old female patient with PLS who had reported with old unaesthetic denture.
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