Endodontic therapy of tooth with necrotic pulp with wide open apex has always posed challenge to endodontists. Endodontic treatment for such teeth is conventional Apexification with or without apical barrier. Traditionally calcium hydroxide has been used for apexification but prolonged treatment time is one of its major disadvantages which was overcome by the use of MTA. However, one of the technical problems faced with this restorative material is to prevent over fill and under fill. Using of a matrix avoids the extrusion of material into the periapical tissues. This article demonstrates the concept of using platelet rich fibrin membrane as an apical matrix barrier for stabilization of MT A in root end Apexification procedure. Platelet Rich Fibrin is an autologous fibrin matrix containing a large quantity of platelet and leukocyte cytokines, which enhance healing by release of growth factor. This case report represents the successful management of caseof immature maxillary anterior teeth with MT A plug and PRF as internal matrix.
Trope M. Treatment of i=ature teeth with non-vital pulps and apical periodontitis. Endod topics 2006; 14:51-59.
Rafter M. Apexification: a review. Dent Traumatol 2005; 21:1-8. Van Hassel HJ, Natkin E. Induction of root end closure. J Dent Children 1970; 37:57-9.
Steiner JC, Dow PR, Cathey GM. Inducing root end closure of non-vital permanent teeth. J Dent Children 1968; 35: 47-54.
Andreasen JO, Farik B, Munksgaard EC. Long-term calcium hydroxide as a root canal dressing may increase risk of root fracture. Dent Traumatol 2002; 18:134-137.
Saunders WP, Saunders EM. Coronal leakage as a cause of failure in root canal therapy. A review. Endod Dent Traumatol 1994;10:105-108.
Steinig TH, Regan JD, Gutmann JL. The use and predictable placement of mineral trioxide aggregate in one-visit apexification cases. Aus Endod J 2003;29:34-42.
Morse DR, Olarnicv J, Yesilsoy C. Apexififcation: review ofliterature. Quntessence Int 1990;21:589-98.
Coveilo J, Brilliant JD. A preliminary clinical study on the use of calcium phoaphate as apical barrier. J Endod 1979;5:6-13.
Schumacher JW, Rutledge RE. An alternative to Apexification. J Endod 1993;19:529-31.
Rossmeisi R, Reader A, Melfi R, Marquard J. A study of freeze dries (lyophilized) cortical bone used as an paical barrier in adult monkey teeth. J endod 1982;8:219-226.
Rossmeisi R, Reader A, Melfi R, Marquard J. A study of freeze dries dentin used as an apical barrier in adult monkey teeth. Oral surgey 1982;53:303-310.
Nevins A, Finkelstein F, Melfi R, Marquard J. Induction of hard tissue into pulpless open apex teeth using collagen calcium phosphate gel. J Endod 1978;4:76-81.
Eleazer PD, Mcdonald TW, Sinai Ill, Fantasia JE, Michelich RJ, TAhiela JA. Proplast as an apical barrier in root canal therapy. J Endod 1984; 10:487-90.
Torabinejad M, Chivian N. Clinical applications of mineral trioxide aggregate. J Endod 1999; 25:197-205.
Torabinejad M, Watson TF, Pitt Ford TR. Sealing ability of a mineral trioxide aggregate when used as a root end filling material. J Endod 1993; 19:591-595.
Felippe WT, Felippe MCS, Rocha MJC. The effect of mineral trioxide aggregate on the apexification and periapical healing of teeth with incomplete root formation. Int Endod J 2009;39:2-9.
Nosrat A, Nekoofar MH, Bolhari B, Dummer PMH. Unintentional extrusion of mineral trioxide aggregate: a report of three cases. Int Endod J 2012;45:1165-1176, 2012.
Dohan DM, Choukran J, Diss A, Dohan SL, Dohan AJ, Mouhyi J etal. Platelet rich fibrin(PRF): A second generation platelet concentrate. Part I: technological concepts and evolution. Oral surg oral med oral pathol oral radiol Endod 2006;101:E37-44.
Sheehy EC, Roberts GJ. Use of calcium hydroxide for apical barrier formationand healing in non-vital immature permanent teeth: a review. Br Dent J 1997; 183(7):241-6
Bargholz C. Perforation repair with mineral trioxide aggregate: a modifiedmatrix concept. Int endod J 2005;38:59-69.
Choukroun J, Diss A, Simonpieri A, Girard MO, Schoeffler C, Dohan SL et al Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part N: clinical effects on tissue healing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:e56--e60
Siqueira JF Jr, Guimaraes-Pinto T, R69as IN. Effects of chemomechanical preparation with 2.5% sodium hypochlorite and intracanal medication with calcium hydroxide on cultivable bacteria in infected root canals. J Endod. 2007;33(7):800-5.
Hillsmann M, Hahn W. Complications during root canal irrigation-literature review and case reports. Int Endod J. 2000;33(3):186-93
Ghaziani P, Aghasizadeh N, Sheikh-Nezami M. Endodontic treatment with MTA apical plugs: a case report. J Oral Sci. 2007;49(4):325-9.
Qualtrough AJ, Mannocci F. Tooth-colored post systems: A review. Oper Dent 2003;28:86-91.