Background: Regeneration of periodontium using autologous materialshave been attempted as it addresses safety issues and ensures easy availability. Among the autologous options available, use of platelet concentrates are promising due to ease of procurement, handling and low cost. Platelet-rich plasma (PRP) is an autologous product that is derived from whole blood through the process of gradient density centrifugation. We hereby report a case of chronic periodontitis with intra bony defects in relation 46 and 47 treated with PRP combined with bone grafts with a six month follow up.
Methodology: 5ml of patient\'s venous blood was collectedand PRP obtained after centrifugation. The platelet concentrate obtained was used in combination with bone graft in intra bony defect in relation to 46 and 47.
Results: A reduction in the Probing pocket depth (PPD) from 7mm (Pre-operative) to 3mm and CAL (clinical attachment level) from 9 mm (Pre-operative) to 5 mm at 6 month recall was observed respectively.
Conclusion: Significant improvement in clinical parameters such as PPD, CAL indicates success of regenerative therapy using PRP with bone grafts.
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