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VOLUME 12 , ISSUE 1 ( January-June, 2022 ) > List of Articles

ORIGINAL RESEARCH

Antimicrobial Effect of Euphorbia hirta on Common Oral Pathogens: In Vitro Study

Prabhu Subramani, Gajalakshmi Ganesh, Devi Mani, Sumathi C Jones

Keywords : Candida albicans, Escherichia coli, Euphorbia hirta, Lactobacillus acidophilus, Streptococcus mutans

Citation Information : Subramani P, Ganesh G, Mani D, Jones SC. Antimicrobial Effect of Euphorbia hirta on Common Oral Pathogens: In Vitro Study. 2022; 12 (1):5-7.

DOI: 10.5005/jp-journals-10083-1015

License: CC BY-NC 4.0

Published Online: 17-12-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Background: Euphorbia hirta is a tropical plant common throughout India. It is used to treat cough, fever, asthma, etc. It has anti-inflammatory and antimicrobial properties. This study was conducted to investigate the antimicrobial activity of E. hirta on common oral pathogens. Materials and methods: An in vitro study was conducted to determine the antimicrobial effect of the ethanol extract of E. hirta on the bacteria (Streptococcus mutans, Lactobacillus acidophilus, and Escherichia Coli) and fungi (Candida albicans). The agar well-diffusion method was used to determine the mean zone of inhibition (ZOI). Results: Euphorbia hirta has antibacterial and antifungal activity against S. mutans (ZOI = 11 ± 0.54 mm), L. acidophilus (ZOI = 10 ± 0.04 mm), E. coli (ZOI = 13 ± 0.05 mm), and C. albicans (ZOI = 14 ± 0.59 mm) at concentration of 5 mg/mL. Conclusion: Euphorbia hirta has antibacterial and antifungal properties against common oral pathogens.


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  1. Lind EM, Tallantire AC. Some common flowering plants of Uganda. Oxford University Press, Nairobi 1971: p. 182.
  2. Rao KVB, Karthik L, Elumalai EK, Srinivasan K, Kumar G. Antibacterial and antifungal activity of Euphorbia hirta leaves: A comparative study. J Pharm Res 2010;3(3):548–549. ISSN: 0974-6943.
  3. Al-Snafi AE. Pharmacology and therapeutic potential of Euphorbia hirta (Syn: Euphorbia pilulifera) – A review. J Pharm 2017;7(3):7–20. DOI: 10.9790/3013-0703010720.
  4. Jensen WB. The origin of Soxhlet extraction. J Clin Edu 2007;9084(12): 1913–1914. DOI: 10.1021/ed084p1913.
  5. Vanitha V, Vijayakumar S, Nilavukkarasi M, Punitha VN, Vidhya E, Praseetha PK. Heneicosane—A novel microbicidal bioactive alkane identified from Plumbago zeylanica L. Ind Crops Prod 2020; 154:112748. https://doi.org/10.1016/j.indcrop.2020.112748.
  6. Uddin SJ, Grice D, Tiralongo E. Evaluation of cytotoxic activity of patriscabratine, tetracosane and various flavonoids isolated from the Bangladeshi medicinal plant Acrostichum aureum. Pharmaceut Biol 2012;50(10):1276–1280. DOI: 10.3109/13880209.2012.673628.
  7. Saravanan R, Dhachinamoorhi D, Sensthikumar K, Srilakshmi M, Divya ST. Antibacterial activity of Euphorbia hirta extracts. Int J Res Ayurveda Pharm 2012;3(3):439–441. Corpus ID: 55279703.
  8. Bansal V, Gupta M, Bhaduri T, Shaikh SA, Sayed FR, Bansal V, et al. Assessment of antimicrobial effectiveness of neem and clove extract against Streptococcus mutans and Candida albicans: An in vitro study. Niger Med J 2019;60(6):285–289. DOI: 10.4103/nmj.NMJ_20_19.
  9. Sharma Y, Gupta Y, Sharma D. Bactericidal activity of different parts of Azadirachta Indica on probiotic microbes. Asian J Pharmaceut Clin Res 2016;9(1):50–53. Corpus ID: 212448705.
  10. Gupta I, Das N, Ranjan P, Sujatha R, Gupta R, Gupta N. A preliminary study on the evaluation of in-vitro inhibition potential of antimicrobial efficacy of raw and commercial honey on Escherichia coli: An emerging periodontal pathogen. Mymensingh Med J 2021;30(2):547–554. PMID: 33830141.
  11. Mauti GO, Mauti EM, Ouno GA, Mabeya BM. Antibacterial activity of garlic, tulsi, bitter guard and cinnamon extracts against wound pathogens. J Sci Innov Res 2015;4(4):178–181.
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